In most cases, yes. Smoke odor lives in fabric (headliner, seats, carpet), in the HVAC duct system, and in any porous interior plastic. Maximum's odor removal pairs deep extraction (steam + enzyme treatment on fabrics) with an ozone treatment that neutralizes odor molecules in places extraction can't reach.
Two things shape outcomes: how long the smoke exposure lasted (months vs years) and whether the headliner was directly affected (the headliner is the hardest to clean in any car). We're upfront after assessment about whether full removal is realistic versus significant reduction.
For just-bought used cars, schedule the treatment within the first week — the longer smoke residue sits, the deeper it sets. $75 for moderate cases; severe cases quoted after assessment.